Faculty of Pharmacy
Main Page
For International Students
Faculty Administration
Dean's OfficeOrganizational ChartVice Deans' Duty AssignmentsFaculty and Administrative BoardsDepartments and Heads of DepartmentFaculty Commissions and CoordinatorshipsFaculty Self-Assessment Committee
About the Faculty
General Introduction to Our FacultyOur Mission and VisionNational Undergraduate AccreditationOur Academic Awards and AchievementsRanking Success and ConditionsInformation BroschureHacettepe University Strategic PlanFaculty of Pharmacy Strategic PlanSelf Assessment ReportsDirectives and PrinciplesStudent Information Broschure
Faculty Staff
Faculty MembersResearch AssistantsLecturersAdministrative StaffDeansFaculty Members Who Have Contributed to Our FacultyOur Retired Administrative Staff
Academic Units
R&D Unit
Hacettepe University Research Priority Areas ReportHacettepe University Pharmacy Practices Unit and R&D Laboratory (HÜNİKAL)HÜEF Pharmacy Simulation–Practice Pharmacies
Announcements and Agenda
Personel Affairs Forms
Student Petition Forms
H.U. Faculty of Pharmacy Alumni Association
Undergraduate Education
Hacettepe University Distance Education PlatformNational Core Curriculum for Pharmacy EducationCurriculumAcademic CalendarCourse ScheduleDirectorate of Student AffairsBİLSİS (Student Information System)RegulationsEU Programs - ERASMUSStudent RepresentativesPrinciples and Guidelines for the Implementation of Undergraduate Internship CoursesUndergraduate Internship DirectiveExamination SchedulesECF 567-568 Graduation Project Principles and Guidelines
Graduate Education
Pharmaceutical Development Society (FGT)
Hacettepe University Journal of the Faculty of Pharmacy
External Links
Activity Reports
Publications-Department of Pharmaceutical Microbiology
  1. Adal, E., Oksuz, Z., Ozkul, C., Nigiz, S., Alagoz, M. A., Dogen, A., Simsek, R., & Algul, O. (2025). Exploring bisbenzimidazole-chalcone hybrid compounds: Dual-action as antibacterial agents targeting biofilm formation and E. Coli DNA gyrase inhibition. Journal of Molecular Structure, 1338, 142375.
  2. Gelen-Gungor, D., Nigiz, Ş., Özkul, C., Eroğlu, H., Nemutlu, E., Ulubayram, K., Mao, Y., Michniak-Kohn, B., & Eroğlu, İ. (2025). Co-delivery of azithromycin and nisin through liposomes for skin infection to reduce antimicrobial drug resistance. International Journal of Pharmaceutics, 679, 125764.
  3. Demir, M., Soki, J., Tanrıverdi, E. S., Özkul, C., Mahmood, B., Otlu, B., & Hazırolan, G. (2024). Molecular characterization and antibiotic resistance of clinical Bacteroides and related genera from a tertiary care center in Türkiye (Turkey). Anaerobe, 90, 102912.
  4. Koçak Aslan, E., Armaković, S. J., Armaković, S., Özenver, N., Özkul, C., & Gündüz, M. G. (2024). Biginelli dihydropyrimidines carrying azole rings: Synthesis, computational studies, and evaluation of alpha‐glucosidase inhibitory and antimicrobial activities. Journal of Molecular Structure, 1306, 137802.
  5. Babayeva A, Ozkul C, Coskun M, Uzun A, Yalcin MM, Yalinay M, Akturk M, Toruner FB, Karakoc MA, Yetkin I, Altinova AE. Alteration in gut microbial characteristics of patients with acromegaly. Endocrine. 2024 May 31:1-9.
  6. Karakas E, Ayhan MS, Karasu O, Kocak CO, Yalinay M. InVivoComparison of the Efficacy and Duration of Local Antibiotics on Smooth, Texturedand Polyurethane Implant Surfaces. Aesthetic Plastic Surgery. 2024 May 28:1-1.
  7. Bekar C, Ozmen O, Ozkul C, Ayaz A. Inulin protects against the harmful effects of dietary emulsifiers on mice gut microbiome. PeerJ. 2024 Mar 21;12:e17110.
  8. Koçak E, Ozkul C, Bozal‐Palabiyik B, Süslü İ, Uslu B. Electrochemical biosensors for rapid diagnosis of bacterial infections: Design, targets and applications in clinical setting. Electroanalysis. 2023 Nov;35(11):e202300106.
  9. Şenkardeş S, Atlıhan İ, Çayır E, Mega Tiber P, Orun O, Nigiz Ş, Özkul C, Gündüz MG, Küçükgüzel ŞG. Synthesisand Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents. Chemistry & Biodiversity. 2023 Aug;20(8):e202300766.
  10. Unal M, Bostanci E, Ozkul C, Acici K, Asuroglu T, Guzel MS. Crohn’s Disease Prediction Using Sequence Based Machine Learning Analysis of Human Microbiome. Diagnostics. 2023 Sep 1;13(17):2835.
  11. Koçak, E., Ozkul, C., Bozal-Palabiyik, B., Süslü, İ., & Uslu, B. (2023). Electrochemical biosensors for rapid diagnosis of bacterial infections: Design, targets and applications in clinical setting. Electroanalysis, 35(11), e202300106.
  12. Han Mİ, Dengiz C, Doğan ŞD, Gündüz MG, Köprü S, Özkul C. Isoquinolinedione-urea hybrids: Synthesis, antibacterial evaluation, drug-likeness, molecular docking and DFT studies. Journal of Molecular Structure 2022; 1252:132007.
  13. Aydin S, Özkul C, Yucel NT, Karaca H. Gut Microbiome Alteration after Reboxetine Administration in Type-1 Diabetic Rats. Microorganisms 2021; 9(9):1948.
  14. Gündüz MG, Kaya B, Özkul C, Şahin O, Rekha EM, Sriram D, Ülküseven B. S-alkylated thiosemicarbazone derivatives: Synthesis, crystal structure determination, antimicrobial activity evaluation and molecular docking studies. Journal of Molecular Structure 2021;1242:130674.
  15. Kocak E, Nemutlu E, Kır S, Sagiroglu M, Özkul C. Integrative proteomics and metabolomics approach to elucidate the antimicrobial effect of simvastatin on Escherichia coli. Biomedical Chromatography 2021; 35(10):e5180.
  16. Doğan ŞD, Gündüz MG, Ugur SB, Doğan H, Özkul C, Çetinkaya Y. Copper‐Oxone Promoted Oxidative C− H Functionalization: Synthesis of 2‐Aminobenzothiazoles and Evaluation of Their Antimicrobial Activities. Chemistry Select 2021; 6:4382-4389.
  17. Özkul C, Hazirolan G. Oxacillinase Gene Distribution, Antibiotic Resistance, and Their Correlation with Biofilm Formation in Acinetobacter baumannii Bloodstream Isolates. Microbial Drug Resistance 2021; 27(5):637-646.
  18. Karakan T, Özkul C, Akkol E, Bilici S, Sobarzo-Sánchez E, Capasso R. Gut-Brain-Microbiota Axis: Antibiotics and Functional Gastrointestinal Disorders. Nutrients 2021;13(2), 389.
  19. Ozkul C, Ruiz VE, Battaglia T, Xu J, Roubaud-Baudron C, Cadwell K, Perez-Perez GI, Blaser MJ. A single early-in-life antibiotic course increases susceptibility to DSS-induced colitis. Genome Medicine 2020; 12(1):65.
  20. Ucar BI, Erikci A, Kosemehmetoglu K, Ozkul C, Iskit, Ucar G, Zeren S. Effects of endothelin receptor blockade and COX inhibition on intestinal I/R injury in a rat model: Experimental research. International Journal of Surgery. 2020; 83:89-97.
  21. Mammadova G, Ozkul C, Yilmaz Isikhan S, Acikgoz A, Yildiz BO. Characterization of Gut Microbiota in Polycystic Ovary Syndrome: Findings from a Lean Population. European Journal of Clinical Investigation 2021; 51(4):e13417.
  22. Gündüz MG, Uğur SB, Güney F, Özkul C, Krishna VS, Kaya S, Sriram D, Doğan ŞD. 1, 3-Disubstituted urea derivatives: Synthesis, antimicrobial activity evaluation and in silico studies. Bioorganic Chemistry 2020; 102:104104.
  23. Polat HK, Bozdağ Pehlivan S, Özkul C, Çalamak S, Öztürk N, Aytekin E, Fırat A, Ulubayram K, Kocabeyoğlu S, İrkeç M, Çalış S. Development of besifloxacin HCl loaded nanofibrous ocular inserts for the treatment of bacterial keratitis: In vitro, ex vivo and in vivo evaluation. Int J Pharm. 2020; 585:119552.
  24. Özkul C, Yalınay M, Karakan T. Structural changes in gut microbiome after Ramadan fasting: a pilot study. Beneficial Microbes. 2020; 11(3): 227-233.
  25. Roubaud-Baudron C, Ruiz VE, Swan AM Jr, Vallance BA, Ozkul C, Pei Z, Li J, Battaglia TW, Perez-Perez GI, Blaser MJ. Long-term effects of early-life antibiotic exposure on resistance to subsequent bacterial infection. MBio. 2019; 10(6):e02820.
  26. Dogan SD, Sümeyye B, Gündüz MG, Özkul C, Krishna VS, Sriram D. Synthesis of Disulfide-Bridged N-Phenyl-N’-(alkyl/aryl/heteroaryl) urea Derivatives and Evaluation of Their Antimicrobial Activities. Chemistry& Biodiversity 2019; 16(12): e190046.
  27. Özkul C, Yalınay M, Karakan T. Islamic fasting leads to an increased abundance of Akkermansia muciniphila and Bacteroides fragilis group: A preliminary study on intermittent fasting. Turk J Gastroenterol. 2019; 30(12):1030-1035.
  28. MG Gündüz, MN Tahir, S Armaković, CÖ Koçak, SJ Armaković. Design, synthesis and computational analysis of novel acridine-(sulfadiazine/sulfathiazole) hybrids as antibacterial agents. Journal of Molecular Structure 2019; 1186:39-49.
  29. Ozkul C, Yalinay M, Karakan T, Yilmaz G. Determination of certain bacterial groups in gut microbiota and endotoxin levels in patients with nonalcoholic steatohepatitis. Turkish Journal of Gastroenterology 2017; 28(5):361-369.
  30. Gultekinoglu M, Sarisozen YT, Erdogdu C, Sagiroglu M, Aksoy EA, Oh YJ, Hinterdorfer P, Ulubayram K. Designing of dynamic polyethyleneimine (PEI) brushes on polyurethane (PU) ureteral stents to prevent infections. Acta Biomaterialia 2015; 21:44-54.
  31. Calamak S, Aksoy EA, Ertas N, Erdogdu C, Sagiroglu M, Ulubayram K. Ag/silk fibroin nanofibers: Effect of fibroin morphology on Ag+ release and antibacterial activity. European Polymer Journal 2015; 67:99-112.
  32. Calamak S, Aksoy EA, Erdogdu C, Sagiroglu M, Ulubayram K. Silver nanoparticle containing silk fibroin bionanotextiles. Journal of Nanoparticle Research 2015; 17(2): 1-9.
  33. Calamak S, Erdogdu C, Ozalp M, Ulubayram K. Silk fibroin based antibacterial bionanotextiles as wound dressing materials. Materials Science and Engineering: C 2014; 43:11-20.
  34. Erdogdu C, Saribas Z, Yilmaz YA. Detection of cagA and vacA genotypes of Helicobacter pylori isolates from a university hospital in Ankara region, Turkey. Turkish Journal of Medical Sciences 2014; 44 (1):126-132.
  35. Saygili N, Ekizoglu M, Erdogdu C. Synthesis of New 2-(N'-Allylidene-hydrazino) quinazolinones and 2-(4,5-Dihydropyrazolyl)-quinazolinones and Their Antimicrobial and Antifungal Activity Screening. Asian J Che 2014; 26:3197-3203.

 

  1. Buehrle DJ, Shields RK, Chen L, Hao B, Press EG, Alkrouk A, Potoski BA, Kreiswirth BN, Clancy CJ, Nguyen MH. Evaluation of the In Vitro Activity of Ceftazidime-Avibactam and Ceftolozane-Tazobactam against Meropenem-Resistant Pseudomonas aeruginosa Isolates. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3227-31.
  2. Türkmen E, Parmaksız S, Nigiz Ş, Sağıroğlu M, Şenel S. A safe bioadhesive system for topical delivery of combined antimicrobials in treatment of skin infections in veterinary medicine. Journal of Drug Delivery Science and Technology. 2023 Feb 1;80:104116.
  3. Koçak E, Nigiz Ş, Özkan E, Erdoğan Kablan SE, Hazirolan G, Nemutlu EM, Kır S, Sağıroğlu M, Özkul C. Exometabolomic analysis of susceptible and multi‐drug resistant Pseudomonas aeruginosa. Letters in Applied Microbiology. 2022 Aug 1;75(2):234-42.
  4. Hazirolan G, Ozkul C. First Report of Plasmid-Mediated fosA6 Harboring Klebsiella pneumoniae Isolate in Turkey. Clinical laboratory. 2022 Nov 1;68(11).
  5. Nigiz Ş, Hazırolan G, Köseoglu Eser Ö, Gür D. First Detection of Klebsiella pneumoniae Isolate Co-Harboring Fosfomycin Resistance Gene fosA3 and blactx-m Among Gram Negative Urine Isolates in a Turkish Hospital. Microbial Drug Resistance. 2022 Mar 1;28(3):317-21.